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Table 4 Agreement between HR and HER2 status from primary and metastatic samples

From: Impact of hormone receptor status on patterns of recurrence and clinical outcomes among patients with human epidermal growth factor-2-positive breast cancer in the National Comprehensive Cancer Network: a prospective cohort study

 

HR status*

HER2*

 
 

ER status

K

(ASE)

PR status

K

(ASE)

HER2 Status

K

(ASE)

Total (N)

126

 

123

 

121

 

Agreement,

N (%)

      

Yes

98 (78)

0.55 (0.074)

86 (70)

0.31 (0.083)

101 (83)

0.003

(0.019)

No

28 (22)

  

37 (29)

 

20 (17)

+ to -

18 (14)

  

30 (24)

 

20 (17)

- to +

10 (8)

  

7 (6)

 

N/A

  1. Note: + to - , change from positive to negative marker; - to +, change from negative to positive marker; ER, estrogen receptor; HER2, Human epidermal growth factor 2; HR, Hormone receptor; PR, progesterone receptor. *Data were available in a limited number of samples due to unknown information in the metastatic setting.