Table 4 SIRs for mothers and sisters by morphology features of the subgroup of 375 index cases.

Number of mitoses >50

Absent

60

28.50

2.11

(1.64 to 2.71)

1.91

(0.83 to 3.87)

0.07

Present

9

2.24

4.02

(2.09 to 7.73)

Nuclear grade - malignant

Absent

10

4.67

2.14

(1.15 to 3.98)

1.06

(0.54 to 2.32)

0.9

Present

59

26.06

2.26

(1.75 to 2.92)

Tubule formation <10

Absent

16

7.86

2.04

(1.25 to 3.32)

1.14

(0.64 to 2.13)

0.7

Present

53

22.87

2.32

(1.77 to 3.03)

Syncytial pattern ≥75%

Absent

64

29.42

2.18

(1.70 to 2.78)

1.75

(0.55 to 4.31)

0.2

Present

5

1.31

3.81

(1.58 to 9.14)

Circumscribed

Absent

51

26.29

1.94

(1.47 to 2.55)

2.09

(1.15 to 3.63)

0.01

Present

18

4.45

4.04

(2.55 to 6.42)

Pushing margins

Absent

66

29.98

2.10

(1.64 to 2.69)

3.76

(1.33 to 8.64)

0.002

Present

6

0.76

7.90

(3.55 to 17.59)

Lymphocytic infiltrate I - diffuse

Absent

38

19.42

1.96

(1.42 to 2.69)

1.40

(0.84 to 2.31)

0.2

Present

31

11.32

2.74

(1.93 to 3.89)

Lymphocytic infiltrate II-intense

Absent

53

25.89

2.05

(1.56 to 2.68)

1.61

(0.86 to 2.86)

0.1

Present

16

4.85

3.30

(2.02 to 5.39)

Glandular growth pattern

Absent

25

7.58

3.30

(2.23 to 4.88)

0.58

(0.34 to 0.98)

0.03

Present

44

23.16

1.90

(1.41 to 2.55)

Lobular growth pattern

Absent

36

18.34

1.96

(1.42 to 2.72)

1.36

(0.82 to 2.24)

0.2

Present

33

12.40

2.66

(1.89 to 3.74)

Trabecular growth pattern

Absent

54

25.90

2.09

(1.60 to 2.72)

1.49

(0.78 to 2.67)

0.2

Present

15

4.84

3.10

(1.87 to 5.15)

Tubular growth pattern

Absent

59

25.25

2.34

(1.81 to 3.02)

0.78

(0.36 to 1.54)

0.5

Present

10

5.49

1.82

(0.98 to 3.39)

Acinar growth pattern

Absent

62

26.10

2.37

(1.85 to 3.04)

0.65

(0.25 to 1.42)

0.3

Present

7

4.56

1.54

(0.73 to 3.22)

Sclerosis - extensive

Absent

8

1.45

5.52

(2.76 to 11.04)

0.38

(0.18 to 0.91)

0.01

Present

61

29.29

2.08

(1.62 to 2.68)

Extensive intraductal carcinoma

Absent

51

25.61

1.99

(1.51 to 2.62)

1.77

(0.97 to 3.06)

0.04

Present

18

5.12

3.51

(2.21 to 5.58)

Necrosis

Absent

48

21.35

2.25

(1.70 to 2.98)

0.99

(0.57 to 1.69)

1.0

Present

21

9.39

2.24

(1.46 to 3.43)

Apoptosis - moderate or intense

Absent

12

6.64

1.81

(1.03 to 3.18)

1.31

(0.69 to 2.68)

0.4

Present

57

24.10

2.37

(1.83 to 3.07)

Lymphatic invasion

Absent

53

21.10

2.51

(1.92 to 3.29)

0.76

(0.35 to 1.17)

0.1

Present

16

9.64

1.66

(1.02 to 2.71)

ER positive

Absent

25

10.00

2.50

(1.69 to 3.70)

0.65

(0.44 to 1.33)

0.3

Present

34

17.85

1.91

(1.36 to 2.67)

PR positive

Absent

26

9.10

2.86

(1.95 to 4.20)

0.70

(0.38 to 1.13)

0.1

Present

35

18.78

1.86

(1.34 to 2.60)