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Table 3 Multivariate modelling of hazard ratios for tumour morphology features of the index cases.

From: Tumour morphology of early-onset breast cancers predicts breast cancer risk for first-degree relatives: the Australian Breast Cancer Family Registry

Feature

Hazard Ratio

(95% CI)

P

Sclerosis - extensive

0.36

(0.20 to 0.65)

0.001

Acinar growth pattern

0.42

(0.22 to 0.78)

0.006

Glandular growth pattern

0.40

(0.25 to 0.65)

<0.001

Extensive intraductal carcinoma

1.96

(1.28 to 3.00)

0.002

Circumscribed

1.85

(1.10 to 3.12)

0.02