Table 2 Paired analysis of receptor expression in breast cancer and brain metastases
Brain metastasis | ||||
|---|---|---|---|---|
Primary tumor | Negative | Positive | Total number (%) | |
ER | Negative, n (%) | 56 (81) | 13 (19) | 69 (100) |
Positive, n (%) | 22 (43) | 29 (57) | 51 (100) | |
Total, n (%) | 78 (65) | 42 (35) | 120 (100) | |
Overall discordance rate (95% CI) | 29% (21% to 38%) | |||
PR | Negative, n (%) | 67 (85) | 11 (15) | 78 (100) |
Positive, n (%) | 23 (56) | 18 (44) | 41 (100) | |
Total, n (%) | 90 (76) | 29 (24) | 119 (100) | |
Overall discordance rate (95% CI) | 29% (21% to 38%) | |||
HER2 | Negative, n (%) | 51 (84) | 10 (16) | 61 (100) |
Positive, n (%) | 7 (12) | 51 (88) | 58 (100) | |
Total, n (%) | 58 (49) | 61 (53) | 119 (100) | |
Overall discordance rate (95% CI) | 14% (9% to 22%) | |||