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Table 2 Paired analysis of receptor expression in breast cancer and brain metastases

From: Conversion of epidermal growth factor receptor 2 and hormone receptor expression in breast cancer metastases to the brain

   Brain metastasis  
Primary tumor Negative Positive Total number (%)
ER Negative, n (%) 56 (81) 13 (19) 69 (100)
  Positive, n (%) 22 (43) 29 (57) 51 (100)
  Total, n (%) 78 (65) 42 (35) 120 (100)
  Overall discordance rate (95% CI) 29% (21% to 38%)
PR Negative, n (%) 67 (85) 11 (15) 78 (100)
  Positive, n (%) 23 (56) 18 (44) 41 (100)
  Total, n (%) 90 (76) 29 (24) 119 (100)
  Overall discordance rate (95% CI) 29% (21% to 38%)
HER2 Negative, n (%) 51 (84) 10 (16) 61 (100)
  Positive, n (%) 7 (12) 51 (88) 58 (100)
  Total, n (%) 58 (49) 61 (53) 119 (100)
  Overall discordance rate (95% CI) 14% (9% to 22%)