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Table 1 Z-scores of top gene hits for siRNA screen in MDA-MB231 cells.

From: Cross-species genomic and functional analyses identify a combination therapy using a CHK1 inhibitor and a ribonucleotide reductase inhibitor to treat triple-negative breast cancer

  MB231 (screen 1) MB231 (screen 2) Hs578T MCF10A
ANLN -3.275 -2.657 -2.139 -2.230
CHEK1 -2.766 -2.441 -4.719 -0.218
KIF11 -2.475 -2.231 -3.832 -2.770
RRM1 -2.637 -2.347 -2.053 -0.955
RRM2 -3.647 -2.915 -2.518 -1.348
TPX2 -1.932 -1.697 -3.864 -1.452