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Table 1 Z-scores of top gene hits for siRNA screen in MDA-MB231 cells.

From: Cross-species genomic and functional analyses identify a combination therapy using a CHK1 inhibitor and a ribonucleotide reductase inhibitor to treat triple-negative breast cancer

 

MB231 (screen 1)

MB231 (screen 2)

Hs578T

MCF10A

ANLN

-3.275

-2.657

-2.139

-2.230

CHEK1

-2.766

-2.441

-4.719

-0.218

KIF11

-2.475

-2.231

-3.832

-2.770

RRM1

-2.637

-2.347

-2.053

-0.955

RRM2

-3.647

-2.915

-2.518

-1.348

TPX2

-1.932

-1.697

-3.864

-1.452