Figure 5
From: Clonal relatedness between lobular carcinoma in situ and synchronous malignant lesions
Representative photomicrographs: Case #95, lobular carcinoma in situ -ductal carcinoma in situ -invasive cancer triplet. (A), (B) Terminal duct lobular units involved by classic lobular carcinoma in situ (LCIS): (A) H & E, 40×; (B) H & E, 100×. (C), (D) High-grade ductal carcinoma in situ (DCIS) with solid and micropapillary patterns: (C) H & E, 40×; (D) H & E, 100×. (E), (F) Focus of high-grade DCIS (arrows) and associated invasive ductal carcinoma of no special type of moderate tubule formation and intermediate nuclear grade - histologic grade II/III: (E) H & E, 40×; (F) H & E, 100×.