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Figure 1 | Breast Cancer Research

Figure 1

From: Breast carcinoma and Lynch syndrome: molecular analysis of tumors arising in mutation carriers, non-carriers, and sporadic cases

Figure 1

Outcome of MSI and IHC analyses in three breast tumors from MLH1 mutation carriers. Left, MLH1 expressing, MSS breast carcinoma from individual 3:60 (Table 2). Middle, ductal carcinoma from the right breast from individual 77:15, displaying MLH1 protein loss and MSI. Right, lobular carcinoma from the left breast of the same patient, showing MLH1 protein loss and stable microsatellites. Red arrow in IHC stainings denotes lack of expression in tumor cells and green arrow positive expression in normal cells. MSI results are based on BAT25. IHC, immunohistory; MSI, microsatellite instability; MSS, microsatellite stable.

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