Figure 10From: JMJD6 is a driver of cellular proliferation and motility and a marker of poor prognosis in breast cancer Decrease of cyclin E2 protein level in JMJD6 knockdown. Western blot detection of G1 cell-cycle cyclins is shown. A decrease in cyclin E2 (CCNE2) level with decrease in JMJD6 levels was evident in MCF-7 and MDA-MB231. Cyclin E1 (CCNE1) and cyclin D1 (CCND1) displayed an inconsistent change on JMJD6 siRNA transfection in both MCF-7 and MDA-MB231 cells.Back to article page