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Table 1 Association of CD44 with molecular characteristics of breast tumors

From: CD44 enhances invasion of basal-like breast cancer cells by upregulating serine protease and collagen-degrading enzymatic expression and activity

 

Association of CD44 expression with tumor characteristics

 
   

n(%)

CD44 n(%)

P

 
 

CD44

+

84/141 (60%)

N/A

  
  

-

57/141 (40%)

N/A

  
 

ER

+

121/140 (86%)

73/121 (60%)

0.025 Mann-Whitney,

0.019 t test

 
  

-

19/140 (14%)

16/19 (84%)

  
 

PR

+

96/140 (69%)

56/96 (58%)

0.021 Mann-Whitney,

0.025 t test

 
  

-

44/140 (31%)

33/44 (75%)

  
 

Her2

+

13/133 (10%)

75/120 (63%)

Not significant

 
  

-

120/133 (90%)

8/13 (62%)

  
 

Basal

+

15/135 (11%)

13/15 (87%)

0.018 Mann-Whitney,

0.021 t test

 
  

-

120/135 (89%)

72/120 (60%)

  
 

Triple negative

+

15/135 (11%)

13/15 (87%)

0.018 Mann-Whitney,

0.021 t test

 
  

-

120/135 (89%)

72/120 (60%)

  
 

Expression of CD44 is expressed as a percentage of patients in individual clinical classifications (first column).

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