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Table 5 Multivariate analysis of factors associated with local-regional control

From: Local-regional control according to surrogate markers of breast cancer subtypes and response to neoadjuvant chemotherapy in breast cancer patients undergoing breast conserving therapy

Factor Hazard Ratio (95% CI) P-value
Subtype*   
HR-/HER2- 5.7 (2.6 to 12.3) < 0.001
HR-/HER2+ 5.7 (2.0 to 16.3) 0.001
≥ 4 positive lymph nodes 2.9 (1.3 to 6.6) 0.01
pCR 0.22 (0.07 to 0.74) 0.01
  1. * HR+/HER2- used as referent. CI, confidence interval; pCR, pathologic complete