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Table 5 Multivariate analysis of factors associated with local-regional control

From: Local-regional control according to surrogate markers of breast cancer subtypes and response to neoadjuvant chemotherapy in breast cancer patients undergoing breast conserving therapy

Factor

Hazard Ratio (95% CI)

P-value

Subtype*

  

HR-/HER2-

5.7 (2.6 to 12.3)

< 0.001

HR-/HER2+

5.7 (2.0 to 16.3)

0.001

≥ 4 positive lymph nodes

2.9 (1.3 to 6.6)

0.01

pCR

0.22 (0.07 to 0.74)

0.01

  1. * HR+/HER2- used as referent. CI, confidence interval; pCR, pathologic complete