From: Local-regional control according to surrogate markers of breast cancer subtypes and response to neoadjuvant chemotherapy in breast cancer patients undergoing breast conserving therapy
Factor
Hazard Ratio (95% CI)
P-value
Subtype*
HR-/HER2-
5.7 (2.6 to 12.3)
< 0.001
HR-/HER2+
5.7 (2.0 to 16.3)
0.001
≥ 4 positive lymph nodes
2.9 (1.3 to 6.6)
0.01
pCR
0.22 (0.07 to 0.74)