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Table 3 Five-year actuarial rates of local-regional control according to clinical and pathological disease status

From: Local-regional control according to surrogate markers of breast cancer subtypes and response to neoadjuvant chemotherapy in breast cancer patients undergoing breast conserving therapy

Factor

5-year LRC rate

P-value

Clinical Stage

  

I/II (n = 475)

95%

0.05

III (n = 120)

90%

 

Number positive nodes*

  

0 to 3 (n = 517)

95%

0.03

≥ 4 (n = 75)

87%

 

pCR

  

No (n = 471)

93%

0.06

Yes (n = 124)

97%

 

LVI

  

No (n = 500)

95%

0.02

Yes (n = 95)

89%

 

Nuclear grade**

  

1 or 2 (n = 198)

97%

0.03

3 (n = 396)

92%

 
  1. * In three patients the number of lymph nodes was unknown. ** In one patient, the nuclear grade was unknown. LRC, local-regional control; LVI, lymphovascular invasion; pCR, pathologic complete response