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Table 3 Five-year actuarial rates of local-regional control according to clinical and pathological disease status

From: Local-regional control according to surrogate markers of breast cancer subtypes and response to neoadjuvant chemotherapy in breast cancer patients undergoing breast conserving therapy

Factor 5-year LRC rate P-value
Clinical Stage   
I/II (n = 475) 95% 0.05
III (n = 120) 90%  
Number positive nodes*   
0 to 3 (n = 517) 95% 0.03
≥ 4 (n = 75) 87%  
pCR   
No (n = 471) 93% 0.06
Yes (n = 124) 97%  
LVI   
No (n = 500) 95% 0.02
Yes (n = 95) 89%  
Nuclear grade**   
1 or 2 (n = 198) 97% 0.03
3 (n = 396) 92%  
  1. * In three patients the number of lymph nodes was unknown. ** In one patient, the nuclear grade was unknown. LRC, local-regional control; LVI, lymphovascular invasion; pCR, pathologic complete response