Table 3 Overview of NFκB-inhibiting drugs and their mechanism of action
From: The interaction between ER and NFκB in resistance to endocrine therapy
Class of NFκB inhibitor | Examples |
|---|---|
Proteasome inhibition | Bortezomib, MG132, ALLN, epoxomicin |
Inhibition of IκB phosphorylation | Pyrolydine dithiocarbamate, BAY11-7082, PS1145, BMS-345541, flavopyridol, parthenolide |
Inhibition of nuclear translocation | Flavopyridol, dehydroxymethylepoxyquinomycin, SN50 peptide |