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Table 3 Overview of NFκB-inhibiting drugs and their mechanism of action

From: The interaction between ER and NFκB in resistance to endocrine therapy

Class of NFκB inhibitor Examples
Proteasome inhibition Bortezomib, MG132, ALLN, epoxomicin
Inhibition of IκB phosphorylation Pyrolydine dithiocarbamate, BAY11-7082, PS1145, BMS-345541, flavopyridol, parthenolide
Inhibition of nuclear translocation Flavopyridol, dehydroxymethylepoxyquinomycin, SN50 peptide
  1. IκB, inhibitor of NFκB.