Figure 1From: Preclinical and clinical studies of estrogen deprivation support the PDGF/Abl pathway as a novel therapeutic target for overcoming endocrine resistance in breast cancerTemporal changes in the expression of the proliferation metagene. The dotted line represents the baseline proliferation metagene for the wt MCF7 cells cultured in E2 (1 nM). E2, estradiol; wt, wild type.Back to article page