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Table 2 Breakdown of Nodal index score by biopsy result (N = 431)

From: Potential for the embryonic morphogen Nodal as a prognostic and predictive biomarker in breast cancer

Characteristic IHC Nodal scoring index category Chi-square
P-value
  0 to 3 4 to 6 9  
  N (%) N (%) N (%)  
Diagnosis     
Benign (N = 293) 125 (43) 150 (51) 18 (6) < 0.00011
Malignant (N = 138) 18 (13) 63 (46) 57 (41)  
Biopsy result (N = 402)     
Benign 103 (43) 122 (51) 15 (6) < 0.00011
Atypia/Hyperplasia 22 (42) 27 (52) 3 (6)  
Invasive 8 (8) 51 (46) 51 (46)  
*Missing 10 (34) 13 (45) 6 (21)  
  1. 1 Mantel-Haenszel
  2. * Not included in calculation