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Table 1 Mutation and single nucleotide polymorphisms (SNPs) of CHD5 in 55 breast cancer samples

From: Chromodomain helicase DNA binding protein 5 plays a tumor suppressor role in human breast cancer

Exon Sequence
alteration
Amino acid
alteration
Allele frequency
    Cell lines Tissues
Mutation     
21 DelG3315 - 1/34 0/76
SNPs     
4* C570T Thr157Met 0/34 3/76
4 G529C Leu 8/34 0/76
7 C1003T Phe 15/34 55/76
8 A1204G Val 16/34 55/76
12 C1957T Tyr 3/34 2/76
15 C2479T Asn 0/34 23/76
16 T2593C Ile 11/34 46/76
22 G3436A Ala 0/34 27/76
31 T4715C Ser1539Pro 26/34 0/76
  1. Notes: 17 cell lines and 38 primary tumors of breast cancer were used. * indicates the novel SNP identified in this study. The rest of the SNPs have been reported in the SNP database (dbSNPs).