Table 1 p53 mutation status and prevalence.

Wild-type p53

No variation*; synonymous variations; intronic variations outside splice sites

435 (83.6%)

Mutated p53

Any variation predicted to modify protein sequence: missense, nonsense, insertion, deletion, variation in splice sites

85 (16.3%)

Subcategorization of mutated p53

   Missense mutation

Protein changed by one amino acid

64 (12.3%)

   Truncating mutation

Nonsense, insertion**, deletion**, variation in splice sites

19 (3.6%)

   Not classified***

2 (0.4%)