From: Analysis of terminal duct lobular unit involution in luminal A and basal breast cancers
 | Average number of acini (tertiles)* | |||||||
---|---|---|---|---|---|---|---|---|
Tumor characteristics | Low | Middle | High | OR (95% CI)** | P** | |||
 | N | % | N | % | N | % |  |  |
Tumor size | Â | Â | Â | Â | Â | Â | Â | Â |
   ≤ 2 cm | 48 | 31.8 | 50 | 33.1 | 53 | 35.1 | Ref |  |
   > 2 cm | 40 | 31.0 | 40 | 31.0 | 49 | 38.0 | 1.15 (0.64, 2.06) | 0.64 |
Axillary node metastases | Â | Â | Â | Â | Â | Â | Â | Â |
   Negative | 54 | 34.2 | 47 | 29.7 | 57 | 36.1 | Ref |  |
   Positive | 32 | 27.1 | 41 | 34.8 | 45 | 38.1 | 1.31 (0.72, 2.38) | 0.37 |
Histology | Â | Â | Â | Â | Â | Â | Â | Â |
   Ductal | 49 | 27.5 | 56 | 31.5 | 73 | 41.0 | Ref |  |
   Lobular | 18 | 40.9 | 14 | 31.8 | 12 | 27.3 | 0.45 (0.20, 1.03) | 0.06 |
   Mixed | 11 | 30.6 | 17 | 47.2 | 8 | 22.2 | 0.47 (0.17, 1.27) | 0.13 |
   Other | 10 | 43.5 | 3 | 13.0 | 10 | 43.5 | 0.79 (0.30, 2.07) | 0.62 |
Tumor grade | Â | Â | Â | Â | Â | Â | Â | Â |
   Well differentiated | 25 | 36.2 | 19 | 27.5 | 25 | 36.2 | Ref |  |
   Moderately differentiated | 43 | 28.5 | 54 | 35.8 | 54 | 35.8 | 1.06 (0.56, 2.13) | 0.88 |
   Poorly differentiated | 20 | 32.8 | 17 | 27.9 | 24 | 39.3 | 0.97 (0.42, 2.25) | 0.95 |
ER | Â | Â | Â | Â | Â | Â | Â | Â |
   Negative | 14 | 17.5 | 27 | 33.7 | 39 | 48.8 | Ref |  |
   Positive | 74 | 36.8 | 63 | 31.3 | 64 | 31.8 | 0.34 (0.17, 0.70) | 0.003 |
PR | Â | Â | Â | Â | Â | Â | Â | Â |
   Negative | 24 | 27.9 | 28 | 32.6 | 34 | 39.5 | Ref |  |
   Positive | 64 | 32.8 | 62 | 31.8 | 69 | 35.4 | 0.76 (0.40, 1.43) | 0.39 |
CK5 | Â | Â | Â | Â | Â | Â | Â | Â |
   Negative | 72 | 34.6 | 64 | 30.8 | 72 | 34.6 | Ref |  |
   Positive | 16 | 22.9 | 24 | 34.3 | 30 | 42.9 | 1.72 (0.85, 3.49) | 0.13 |
EGFR | Â | Â | Â | Â | Â | Â | Â | Â |
   Negative | 79 | 34.1 | 78 | 33.6 | 75 | 32.3 | Ref |  |
   Positive | 9 | 19.1 | 10 | 21.3 | 28 | 59.6 | 2.78 (1.21, 6.39) | 0.02 |