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Table 3 Prognosis of up-regulated HSP90 in different subtypes of breast cancer.

From: Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer

Subtype

Event phenotype

Kaplan-Meier survival analysis

COXPH survival analysis

  

P-value

HR (95%CI)

n

P-value

Co-efficiency

P-adjusted

n

All samples

Death

0.0034

1.57 (1.16-2.12)

1072

0.0007

0.5714

0.0062

421

HER2+

Death

0.3118

1.40 (0.73-2.71)

194

0.2564

0.7433

0.1405

63

 

Recurrence

0.475

0.87 (0.58-1.29)

204

0.9528

-0.2160

0.6705

72

 

Distant metastasis

0.2292

0.77 (0.50-1.18)

347

0.5383

-0.6461

0.2330

90

HER2-/ER+

Death

0.0148

1.71 (1.11-2.63)

506

0.0003

0.8373

0.0042

228

 

Recurrence

0.0183

1.31 (1.05-1.65)

832

0.1790

0.2077

0.3054

361

 

Distant metastasis

0.0002

1.65 (1.27-2.15)

1223

0.0098

0.4050

0.0705

415

TNBC

Death

0.0604

1.76 (0.98-3.19)

282

0.5693

0.2586

0.5869

105

 

Recurrence

0.0002

2.29 (1.49-3.52)

285

0.0008

0.9924

0.0101

122

 

Distant metastasis

0.0195

1.60 (1.08-2.37)

516

0.6722

-0.0323

0.9390

158

  1. CI: confidence interval; HR: hazard ratio; n: number of samples