ER and PR signaling nodes during mammary gland development

Breast Cancer Research

Table 1 Genes that are part of the estrogen receptor alpha-positive breast tumor expression signatures

Gene	Extended gene name	Perou and colleagues [11]	West and colleagues [99]	Gruvberger and colleagues [100]	Dressman and colleagues [101]	Van't Veer and colleagues [102]	Sotiriou and colleagues [103]	Schneider and colleagues [104]	Tozlu and colleagues [105]	Wilson and colleagues [106]
GATA-3	Gata binding protein 3	✓	✓	✓		✓	✓	✓	✓
FOXA-1	Forkhead box A 1/HNF 3a	✓	✓		✓	✓		✓	✓	✓
XBP-1	X-box binding protein 1	✓	✓		✓	✓	✓		✓
LIV-1	Solute carrier family 39 member 6		✓		✓	✓	✓	✓	✓	✓
TFF3	Trefoil factor 1		✓	✓	✓	✓	✓		✓	✓
TFF1	Trefoil factor 1		✓		✓				✓	✓
SLC1A4	Solute carrier family 1 member 4							✓		✓
SLC7A2	Solute carrier family 7 member 2								✓	✓
CNND1	Cyclin D1			✓		✓			✓
vmyb	v-myb avian myeloblastosis viral oncogene homolog		✓			✓	✓		✓
Runx1	Runt-related transcription factor 1						✓			✓
BCL-2	B-cell CLL/lymphoma 2					✓	✓
SLC7A5	Solute carrier family 7 member 5			✓			✓
STC2	Stanniocalcin 2			✓		✓

Examples of studies identifying genes that characterize estrogen receptor alpha-positive breast tumors. The table shows genes that appear in more than one study.

ISSN: 1465-542X