SNPa | Genomic locationb | Stage | Number of cases | Number of controls | MAF in cases | MAF in controls | HWE P | Heterozygote OR (95% CI)a | Homozygote OR (95% CI)a | Per-allele OR (95% CI)c | P trend d |
---|---|---|---|---|---|---|---|---|---|---|---|
rs13393577 | 213,005,108 | I | 2,269 | 1,992 | 0.066 | 0.039 | 0.25 | 1.72 (1.38-2.13) | 2.25 (0.79-6.42) | 1.68 (1.38-2.06) | 4.8 × 10-7 |
(C/T) | (2q34) | II | 2,037 | 2,166 | 0.096 | 0.066 | 0.22 | 1.39 (1.16-1.67) | 5.57 (2.26-13.7) | 1.51 (1.29-1.78) | 1.1 × 10-5 |
 |  | III | 1,952 | 1,644 | 0.061 | 0.047 | 0.83 | 1.35 (1.07-1.70) | 2.70 (0.81-9.03) | 1.38 (1.11-1.71) | 1.3 × 10-2 |
 |  | Combined | 6,258 | 5,802 | 0.074 | 0.051 |  | 1.47 (1.28-1.70) | 3.49 (1.93-6.33) | 1.53 (1.37-1.70) | 8.8 × 10-14 |
rs9498283 | 149,646,875 | I | 2,266 | 2,051 | 0.451 | 0.500 | 0.08 | 0.79 (0.68-0.91) | 0.67 (0.56-0.79) | 0.81 (0.75-0.89) | 5.3 × 10-6 |
(A/G) | (6q25.1) | II | 2,049 | 2,145 | 0.449 | 0.470 | 0.05 | 0.97 (0.84-1.12) | 0.85 (0.71-1.01) | 0.92 (0.85-1.01) | 6.8 × 10-1 |
 |  | III | 1,988 | 1,657 | 0.453 | 0.478 | 0.28 | 1.02 (0.87-1.19) | 0.85 (0.70-1.03) | 0.93 (0.84-1.02) | 1.6 × 10-1 |
 |  | Combined | 6,303 | 5,853 | 0.451 | 0.451 |  | 0.92 (0.79-1.07) | 0.78 (0.66-0.92) | 0.89 (0.82-0.96) | 9.6 × 10-3 |
rs11077488 | 65,801,677 | I | 2,273 | 2,052 | 0.150 | 0.185 | 0.58 | 0.77 (0.67-0.89) | 0.60 (0.41-0.86) | 0.77 (0.69-0.87) | 1.2 × 10-5 |
(C/T) | (17q24.3) | II | 2,046 | 2,141 | 0.155 | 0.171 | 0.93 | 0.88 (0.76-1.01) | 0.87 (0.60-1.27) | 0.90 (0.80-1.01) | 9.7 × 10-1 |
 |  | III | 1,984 | 1,669 | 0.164 | 0.163 | 0.90 | 1.02 (0.87-1.18) | 0.98 (0.65-1.49) | 1.01 (0.89-1.15) | 1.1 × 10-1 |
 |  | Combined | 6,303 | 5,862 | 0.156 | 0.174 |  | 0.88 (0.76-1.02) | 0.79 (0.59-1.07) | 0.89 (0.76-1.03) | 1.6 × 10-1 |
rs3806685 | 180,522,445 | I | 2,262 | 2,051 | 0.156 | 0.189 | 0.95 | 0.90 (0.79-1.03) | 0.25 (0.15-0.41) | 0.78 (0.69-0.88) | 3.4 × 10-5 |
(A/G) | (3q26.32) | II | 2,040 | 2,163 | 0.169 | 0.177 | 0.11 | 0.84 (0.73-0.97) | 1.04 (0.72-1.52) | 0.90 (0.80-1.01) | 9.7 × 10-1 |
 |  | III | 1,971 | 1,657 | 0.189 | 0.162 | 0.93 | 1.22 (1.05-1.42) | 1.24 (0.83-1.83) | 1.18 (1.04-1.34) | 1.8 × 10-2 |
 |  | Combined | 6,273 | 5,871 | 0.171 | 0.177 |  | 0.97 (0.78-1.21) | 0.69 (0.28-1.70) | 0.94 (0.74-1.18) | 5.9 × 10-1 |