Regional association plot of the 2q34 (rs13393577) locus. The results of association signals (-log P) are shown for directly genotyped (diamonds) and imputed (triangle) single-nucleotide polymorphisms (SNPs) distributed in a genomic region 500 kb to either side of rs1339577. Red reflects the linkage disequilibrium (r2) with the top SNP, and increasing red hue is associated with increasing r2. The blue bars show the recombination rate based on HapMap phase II release 22 JPT and CHB populations. The bottom panels illustrate the locations of known genes. The genomic position is based on the UCSC (University of California at Santa Cruz) Genome Browser assembly, March 2010. CHB, Han Chinese from Beijing; JPT, Japanese from Tokyo.