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Table 2 Genes mapping to the 19q12 region of amplification

From: Functional characterization of the 19q12 amplicon in grade III breast cancers

Gene symbol Gene name Position (kb) Copy number and expression Pearson's correlation (r) Overexpressed when amplified
(MWU) P-value
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 29,698 to 29,704 0.65* 0.0018
VSTM2B V-set and transmembrane domain containing 2B 30,017 to 30,055 NA NA
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) 30,097 to 30,107 0.77* 0.0018
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 30,156 to 30,166 0.44* 0.0868
C19ORF12 Uncharacterised protein C19ORF12 30,190 to 30,206 0.63* 0.0018
CCNE1 Cyclin E1 30,303 to 30,315 0.66* 0.0071
C19ORF2 RPB5-mediating protein 30,433 to 30,507 0.81* 0.0001
ZNF536 Zinc finger protein 536 30,863 to 31,049 -0.03 0.6064
TSHZ3 Teashirt zinc finger homeobox 3 31,766 to 31,840 0.08 0.5426
  1. Position refers to the genomic location from the Ensembl genome browser based on the February 2009 hg19 build of the genome
  2. • P < 0.05; significant P-values are highlighted in bold; MWU (Mann-Whitney U test).