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Table 2 Pathway analysis of enriched ontological categories, major gene clusters demarcated in Figure 1

From: Gene expression in extratumoral microenvironment predicts clinical outcome in breast cancer patients

Category

Function annotation

Adjusted P-valuea

Highly expressed in Active

  

Cellular Movement

Movement of cells

3.94E-17

 

Homing of cells

3.17E-07

 

Chemotaxis of cells

6.23E-07

 

Infiltration of cells

4.22E-05

Inflammatory Response

Inflammatory response

3.09E-15

 

Infiltration by neutrophils

1.91E-04

 

Recruitment of macrophages

4.24E-04

Connective Tissue Disorders

Connective tissue disorder

6.22E-15

Organismal Injury and Abnormalities

Fibrosis

2.63E-07

Highly expressed in Inactive

  

Cell-to-Cell Signaling and Interaction

Adhesion of cells

3.38E-06

 

Formation of cell-cell contacts

1.41E-03

 

Formation of tight junctions

1.96E-02

 

Formation of intercellular junctions

2.40E-02

Cellular development

Differentiation of epithelial cells

1.08E-03

 

Maturation of epithelial cells

8.05E-03

 

Differentiation of epithelial tissue

5.13E-02

Tissue Development

Morphogenesis of epithelial tissue

6.13E-03

  1. aBenjamini-Hochberg adjusted P-values calculated in Ingenuity Pathway Analysis.