Table 3 Hazards for breast cancer-specific survival with multivariate analysis in the luminal A, luminal B, and HER2⁺/ER^- intrinsic subgroups

Age

1.38

1.04

1.13

≥ 50 vs. < 50 years

(1.02-1.86)

0.037

(0.81-1.35)

0.750

(0.75-1.70)

0.564

Grade

1.75

1.28

2.13

3 vs. 1 and 2

(1.36-2.25)

< 0.001

(0.99-1.67)

0.062

(1.21-3.76)

0.009

Tumor size

1.64

1.49

1.73

> 2 vs. ≤ 2 cm

(1.28-2.11)

< 0.001

(1.14-1.95)

0.004

(1.11-2.68)

0.015

Nodal status

2.20

1.75

1.75

Positive vs. negative

(1.65-2.95)

< 0.001

(1.31-2.32)

< 0.001

(1.07-2.83)

0.025

Lymphovascular invasion

1.12

1.33

1.36

Positive vs. negative

(0.84-1.49)

0.444

(0.99-1.77)

0.056

(0.84-2.18)

0.211

iTIL

1.14

0.85

0.76

≥ 1 vs. 0

(0.86-1.50)

0.357

(0.66-1.11)

0.235

(0.50-1.15)

0.194