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Table 1 Patients included in ATM analyses

From: Low expression levels of ATM may substitute for CHEK2 /TP53 mutations predicting resistance towards anthracycline and mitomycin chemotherapy in breast cancer

Cohort

ATM coding region

ATM promoter

 

No.

Therapy

Mutations

mRNA levels

Copy no.

Mutations

Methylation

Survival

  

n

n

n

n

n

n

1

Doxorubicin

70

69

69

70

-

69

 

FUMI

      

2

Epirubicin

41

1091

-

41

1091

1091

3

Paclitaxel

38

1142

-

38

-

1142

  1. 1 Among the 109 patients, two were omitted from statistical analyses as protocol violators.
  2. 2 Among the 114 patients, 8 had non-evaluable response to therapy.