Figure 2
From: ER and HER2 expression are positively correlated in HER2 non-overexpressing breast cancer
Relation of RNA levels. (a) Relation of ER RNA levels (qRT-PCR) with protein expression assessed with IHC (H score). (b) ER RNA levels according to IHC status. ER-ve (IHC H score ≤ 1); n = 84; and ER+ve (IHC H score > 1); n = 173. (c) Relation of HER2 RNA levels (qRT-PCR) with HER2 amplification levels (FISH). HER2+ve, n = 34; HER2-ve, n = 199; and HER2 equivocal, n = 3. (d) HER2 RNA levels according to IHC HercepTest categories. IHC 0, n = 96; IHC 1+, n = 101; IHC 2+, n = 19; and IHC 3+, n = 37. Means with 95%CI are shown. CI, confidence interval; ER, estrogen receptor; FISH, fluorescence in situ hybridization; HER2, human epidermal growth factor receptor 2; IHC, immunohistochemistry; qRT-PCR, quantitative reverse-transcription polymerase chain reaction.