Skip to main content

Table 1 Characteristics of study population by lobule type in women with benign breast disease

From: Insulin-like growth factor-1, insulin-like growth factor binding protein-3 and lobule type in the Nurses' Health Study II

 

No type 1 lobules or mixed lobule types (n= 398)

Predominant type 1 and no type 3 lobules (n= 74)

Age at biopsy (years)

41.5 (4.6)

44.2 (5.8)

Body mass index (kg/m2)

25.6 (5.7)

28.0 (8.0)

Parity (among parous)

2.3 (0.8)

2.4 (1.0)

Age at first birth (among parous)

26.2 (4.1)

26.2 (4.7)

Height

64.8 (2.5)

64.5 (2.2)

Nulliparous

62 (15.6%)

20 (27.0%)

Family history of breast cancer

46 (11.6%)

6 (8.1%)

Ever use oral contraceptive

332 (83.4%)

64 (86.5%)

Menopausal status

  

   Premenopausal/dubious

343 (86.2%)

54 (73.0%)

   Postmenopausal, no PMH

41 (10.3%)

15 (20.3%)

   Postmenopausal, PMH

14 (3.5%)

5 (6.8%)

Alcohol

  

   None

176 (44.2%)

25 (33.8%)

   0 to < 1.5 g/day

68 (17.1%)

15 (20.3%)

   1.5 to < 4.5 g/day

85 (21.4%)

14 (18.9%)

   4.5+ g/day

69 (17.3%)

20 (27.0%)

Age at menarche

  

   < 11 years

81 (20.4%)

18 (24.3%)

   12 years

123 (30.9%)

22 (29.7%)

   13 years

113 (28.4%)

19 (25.7%)

   14+ years

81 (20.4%)

15 (20.3%)

Histologic categories of benign breast disease

 

   Proliferative with no atypia

365 (91.7%)

65 (87.8%)

   Atypical hyperplasia

33 (8.3%)

9 (12.2%)

Insulin-like growth factor 1

  

   Quartile 1

93 (23.4%)

24 (32.4%)

   Quartile 2

98 (24.6%)

20 (27.0%)

   Quartile 3

98 (24.6%)

20 (27.0%)

   Quartile 4

109 (27.4%)

10 (13.5%)

Insulin-like growth factor binding protein-3

 

   Quartile 1

95 (23.9%)

22 (29.7%)

   Quartile 2

99 (24.9%)

19 (25.7%)

   Quartile 3

101 (25.4%)

17 (23.0%)

   Quartile 4

103 (25.9%)

16 (21.6%)

  1. Data from the Nurses' Health Study II (1991 to 2002) presented as mean (standard deviation) or n (%). PMH, postmenopausal hormones.