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Figure 1 | Breast Cancer Research

Figure 1

From: Aromatase inhibitors, estrogens and musculoskeletal pain: estrogen-dependent T-cell leukemia 1A (TCL1A) gene-mediated regulation of cytokine expression

Figure 1

Effect of estradiol concentration on mRNA expression for cytokine receptors in lymphoblastoid cell line SNPs. Effect of estradiol (E2) concentration on mRNA expression for (A) T-cell leukemia 1A (TCL1A), (B) IL-17RA, (C) IL-17, (D) IL-12RB2, (E) IL-12 and (F) IL-1R2 in Human Variation Panel lymphoblastoid cell lines with wild type (WT) (n = 3) or variant (V) (n = 3) SNP sequences. *P < 0.05 and **P < 0.001 compared with zero E2, +P < 0.05 and ++P < 0.01 for differences between WT and V SNP genotypes at the same E2 concentrations.

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