Site of Mutation | Effect | PLK Neg (0-3) | PLK1 Pos (4-18) |
---|---|---|---|
Exon 4 | Deletion | 1 | 0 |
Exon 5 | Missense | 11 | 6 |
 | Nonsense | 1 | 0 |
Exon 6 | Missense | 5 | 0 |
 | Nonsense | 2 | 1 |
Exon 7 | Deletion | 7 | 2 |
Exon 8 | Missense | 9 | 2 |
Exon 9 | Nonsense | 1 | 0 |
Exon 10 | Deletion | 1 | 0 |
 | Missense | 2 | 0 |
Intron 5 | Frame Shift | 2 | 0 |
Intron 6 | Frame Shift | 1 | 1 |
Intron 9 | Frame Shift | 1 | 0 |
*Exon 5 and 6 | Missense, Silent | 1 | 0 |
*Exon 7, 8 and 9 | Missense, Missense, Silent | 1 | 0 |
 |  | 46 | 12 |