Figure 3From: Immunohistochemical detection of Polo-like kinase-1 (PLK1) in primary breast cancer is associated with TP53mutation and poor clinical outcomePhotomicrographs of PLK1 immunohistochemistry from tissue microarray. A and B Grade 3 invasive ductal carcinoma showing a heterogeneous pattern of nuclear and cytoplasmic staining at low (A) and high (B) power. C and D grade 3 invasive ductal carcinoma showing similar staining but in fewer cells at low (C) and high (D) power. The staining is highly specific and confined to the carcinoma cells. There is no staining of vascular, stromal or lymphoid cells.Back to article page