Targeting of the non-mutated tumor antigen HER2/neu to mature dendritic cells induces an integrated immune response that protects against breast cancer in mice

Table 1 Identification of CD4⁺ T-cell responding peptides in C57BL/6 mice

Peptide pool	Responding 15-mer peptide	Position	Sequence	IFNγ spots per 3 × 10⁵ CD4⁺ T cells
3	p72	284-298	NPEGRYTFGASCVTA	206 ± 20.8
4	p73	288-302	RYTFGASCVTACPYN	503 ± 183.5
5	p104	405-423	EITGYLYISAWPDSL	34 ± 7.5
	p105	409-427	YLYISAWPDSLPDLS	27 ± 13.6
	p108	421-435	DLSVFQNLQVIRGRI	25 ± 7.5
	p109	425-438	FQNLQVIRGRILHN	24 ± 7.3
7	p148	571-585	NGSVTCFGPEADQCV	43 ± 12.3

ISSN: 1465-542X