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Table 2 Signal-to-noise ratio approach results published to date

From: In vivo proton magnetic resonance spectroscopy of breast cancer: a review of the literature

Study n Type tCho SNR method Sensitivity Specificity
Tse et al. 2003 [50] 40 SV ≥2 malignant 89% 100%
Huang et al. 2004 [6] 50 SV ≥2 malignant 100% 67%
Jacobs et al. 2004 [17] 15 MRSI ≥5 malignant 87% 85%
Bartella et al. 2006 [51] 57 SV ≥2 malignant 100% 88%
Bartella et al. 2007 [52] 32 SV ≥2 malignant 100% 85%
Baek et al. 2008 [8] 36 MRSI >3.2 malignant 81% 78%
Hu et al. 2008 [15] 9 MRSI >3 malignant 100% 100%
Tozaki et al. 2009 [53] 171 SV ≥2 malignant 44% 85%
Danishad et al. 2010 [20] 25 MRSI ≥2 malignant 100% NA
Bathen et al. 2011 [54] 40 SV ≥2 malignant 60% NA
  1. n = number of participants. MRSI, magnetic resonance spectroscopic imaging; NA, not applicable; SV, single-voxel; tCho, total choline-containing resonance.