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Table 1 Summary of qualitative 1H-MRS literature published to date

From: In vivo proton magnetic resonance spectroscopy of breast cancer: a review of the literature

Study

n

Technique

Sensitivity

Specificity

PPV

Roebuck et al. 1998 [3]

17

SV

70%

86%

88%

Gribbestad et al. 1998 [23]

22

SV

50%

100%

100%

Kvistad et al. 1999 [4]

40

SV

82%

61%

82%

Cecil et al. 2001 [24]

38

SV

83%

87%

90%

Yeung et al. 2001 [25]

30

SV

92%

83%

97%

Jagannathan et al. 2001 [5]

46

SV

81%

86%

93%

Kim et al. 2003 [26]

35

SV

100%

100%

100%

Joe et al. 2005 [27]

15

SV

100%

NA

NA

Stanwell et al. 2005 [28]

64

SV

80%

86%

84%

Jacobs et al. 2005 [18]

9

MRSI

80%

100%

100%

Geraghty et al. 2008 [29]

16

SV

88%

NA

NA

Baltzer et al. 2011 [30]

62

SV

62%

86%

90%

Chen et al. 2011 [31]

62

SV

73%

NA

NA

  1. n = number of participants. 1H-MRS, magnetic resonance spectroscopy; MRSI, magnetic resonance spectroscopic imaging; NA, not applicable; PPV, positive predictive value; SV, single-voxel.