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Figure 1 | Breast Cancer Research

Figure 1

From: BRCA1 as tumor suppressor: lord without its RING?

Figure 1

BRCA1 domain organization and structure. (a) Domain organization of BRCA1 showing the amino-terminal RING and carboxy-terminal BRCT repeats. (b) Nuclear magnetic resonance structure of the heterodimer formed between the BRCA1 and BARD1 RING domains. The E2 enzyme interacts with the BRCA1 RING domain but not with the BARD1 RING domain [4]. Mutated residues are indicated.

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Breast Cancer Research

ISSN: 1465-542X

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