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Table 3 Reclassification for the Swe-Gail model compared with the full model, based on cut-off values determined by first and third quartile of predicted risk by the Gail model.

From: Breast cancer risk prediction and individualised screening based on common genetic variation and breast density measurement

Control subjects

Full model

   

Swe-Gail model

Low risk (< 2.41%)

Intermediate risk (2.41%-4.11%)

High risk (> 4.11%)

Reclassified (%)

Low risk (< 2.41%)

170

20

10

15

Intermediate risk (2.41%-4.11%)

236

182

62

62

High risk (> 4.11%)

20

65

91

48

Cases subjects

Full model

   

Swe-Gail model

Low risk (< 2.41%)

Intermediate risk (2.41%-4.11%)

High risk (> 4.11%)

Reclassified (%)

Low risk (< 2.41%)

155

53

17

31

Intermediate risk (2.41%-4.11%)

161

225

103

54

High risk (> 4.11%)

14

97

192

37

Total sample

Full model

   

Swe-Gail model

Low risk (< 2.41%)

Intermediate risk (2.41%-4.11%)

High risk (> 4.11%)

Reclassified (%)

Low risk (< 2.41%)

325

72

27

24

Intermediate risk (2.41%-4.11%)

397

407

165

58

High risk (> 4.11%)

34

162

283

41