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Table 2 Summary of the STAT1 staining results on normal breast tissues and paired breast tumors

From: STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas

   Normal breast tissues Breast tumors
Case ERαa Percentage of STAT1+ epithelial cellsb STAT1 staining intensityc STAT1 scored Percentage of STAT1+ neoplastic cellsb STAT1 staining intensityc STAT1 scored
HN1 NA 4 2 6 NA NA NA
HN2 NA 4 1 5 NA NA NA
HN3 NA 4 2 6 NA NA NA
HN4 NA 3 1 4 NA NA NA
HN5 NA 4 2 6 NA NA NA
87 + 4 2 6 1 1 2
160 + 4 2 6 1 1 2
84 + 4 2 6 1 1 2
147 + 4 2 6 1 1 2
80 + 4 2 6 1 1 2
115 + 4 2 6 1 1 2
161 + 3 2 5 1 1 2
58 - 3 1 4 1 1 2
20 - 3 1 4 1 1 2
53 - 4 2 6 1 2 3
47 - 4 2 6 1 2 3
  1. Normal breast tissues from healthy individuals: HN1, HN2, HN3, HN4, and HN5. Paired tumor samples with adjacent normal breast tissues: case 87, 160, 84, 147, 80, 115, 161, 58, 20, 53, and 47. aEstrogen receptor-alpha (ERα) expression in breast tumors. bPercentage score: 1, < 5%; 2, 5%-25%; 3, 26%-75%; 4, > 75%. cIntensity score: 1 = low, 2 = intermediate, 3 = high. dSTAT1 score = percentage score + intensity score. +, positive; -, negative; NA, not applicable.