STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas

Breast Cancer Research

Table 2 Summary of the STAT1 staining results on normal breast tissues and paired breast tumors

		Normal breast tissues			Breast tumors
Case	ERα^a	Percentage of STAT1⁺ epithelial cells^b	STAT1 staining intensity^c	STAT1 score^d	Percentage of STAT1⁺ neoplastic cells^b	STAT1 staining intensity^c	STAT1 score^d
HN1	NA	4	2	6	NA	NA	NA
HN2	NA	4	1	5	NA	NA	NA
HN3	NA	4	2	6	NA	NA	NA
HN4	NA	3	1	4	NA	NA	NA
HN5	NA	4	2	6	NA	NA	NA
87	+	4	2	6	1	1	2
160	+	4	2	6	1	1	2
84	+	4	2	6	1	1	2
147	+	4	2	6	1	1	2
80	+	4	2	6	1	1	2
115	+	4	2	6	1	1	2
161	+	3	2	5	1	1	2
58	-	3	1	4	1	1	2
20	-	3	1	4	1	1	2
53	-	4	2	6	1	2	3
47	-	4	2	6	1	2	3

Normal breast tissues from healthy individuals: HN1, HN2, HN3, HN4, and HN5. Paired tumor samples with adjacent normal breast tissues: case 87, 160, 84, 147, 80, 115, 161, 58, 20, 53, and 47. ^aEstrogen receptor-alpha (ERα) expression in breast tumors. ^bPercentage score: 1, < 5%; 2, 5%-25%; 3, 26%-75%; 4, > 75%. ^cIntensity score: 1 = low, 2 = intermediate, 3 = high. ^dSTAT1 score = percentage score + intensity score. +, positive; -, negative; NA, not applicable.

ISSN: 1465-542X