Figure 2

Bone mineral density change (%) from baseline after 2 years. Figure shows relative change from baseline of BMD (mean (SD)). BMD changes on tibolone compared with placebo between baseline and 2 years of treatment. Tibolone significantly increased BMD, whereas patients taking placebo had a 2% loss of BMD and had a lower weight and height. Overall, a 1.6% increase was found in BMD at lumbar spine on tibolone and a 1.6% BMD loss on placebo, and similar magnitudes of change were seen at the hip (both P ≤ 0.01).