Skip to main content

Table 4 David Enriched Gene Ontology Categories in Genes Expressed Differently between patient tumors and xenografts

From: Molecular profiling of patient-derived breast cancer xenografts

Gene Ontology Biologic Process Count % List Total Fold Enrichment Benjamini
immune response 98 16.2 479 4.01 8.12E-30
cell adhesion 94 15.6 479 3.79 9.26E-27
biologic adhesion 94 15.6 479 3.79 6.90E-27
response to wounding 80 13.2 479 4.26 7.08E-26
defense response 72 11.9 479 3.31 1.51E-16
inflammatory response 49 8.1 479 4.26 7.35E-15
blood vessel development 41 6.8 479 4.73 1.62E-13
vasculature development 41 6.8 479 4.61 2.48E-13
extracellular matrix organization 26 4.3 479 7.06 4.28E-12
positive regulation of immune system process 35 5.8 479 4.15 8.12E-10
extracellular structure organization 28 4.6 479 4.85 4.15E-09
wound healing 30 5.0 479 4.44 6.13E-09
blood vessel morphogenesis 31 5.1 479 4.15 1.38E-08
positive regulation of response to stimuli 32 5.3 479 3.83 4.73E-08
regulation of response to external stimulus 26 4.3 479 4.62 5.46E-08
taxis 26 4.3 479 4.59 5.87E-08
chemotaxis 26 4.3 479 4.59 5.87E-08
angiogenesis 25 4.1 479 4.77 5.70E-08
regulation of cell activation 27 4.5 479 4.36 7.17E-08
regulation of cell migration 26 4.3 479 4.34 1.61E-07
skeletal system development 36 6.0 479 3.19 3.25E-07
regulation of locomotion 27 4.5 479 3.97 4.70E-07
regulation of cell motion 27 4.5 479 3.95 5.01E-07
regulation of T cell activation 21 3.5 479 5.07 4.87E-07
  1. Enriched Gene Ontology Categories in Genes Expressed Differently between patient tumors and xenografts and common to 10 to 13 pairs (first 25 categories represented). BP, biologic process