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Table 3 Molecular subtype classification of primary tumors and corresponding xenografts at later generations

From: Molecular profiling of patient-derived breast cancer xenografts

Tumor code

Origin

Molecular subtype

HBC(x)-3

patient

LumA

 

xenograft p2

LumB

 

xenograft p6

LumA

HBC(x)-5

patient

LumA

 

xenograft p2

LumB

 

xenograft p5

LumB

HBC(x)-6

patient

Basal

 

xenograft p0

Basal

 

xenograft p6

Unclassified

HBC(x)-7

patient

Unclassified

 

xenograft p7

Unclassified

 

xenograft p9

Unclassified

HBC(x)-10

xenograft p4

Basal

 

xenograft p8

Basal

 

patient

Basal

HBC(x)-13

patient

LumA

 

xenograft p6

Unclassified

HBC(x)-15

patient

Normal

 

xenograft p1

Basal

 

xenograft p5

Basal

HBC(x)-12A

patient (primary tumor)

Normal

 

xenograft (primary) p8

Unclassified

 

xenograft (primary) p5

Basal

HBC(x)-12B

patient (metastasis)

Unclassified

 

xenograft (meta) p3

Basal

 

xenograft (meta) p6

Basal

HBC(x)-19

patient

LumA

 

xenograft

LumA

  1. HBC, human breast cancer; HBC-n, HBC primary tumor n; HBCx-n, HBC xenograft tumor; LumA, luminal A; LumB, luminal B; meta, metastasis; P, passage