Array CGH profiles of patient tumors (top) and xenografts (bottom) compared with normal DNA. Recurrence of copy number alterations is plotted on the y-axis and each probe is aligned along the x-axis in chromosomal order. Loss, gain or amplification of gene copy numbers are depicted in green, red and blue, respectively. A, array CGH profile of a luminal tumor. B, array CGH profile of a triple-negative tumor. CGH, comparative genomic hybridization, HBC, human breast cancer, HBC-n, HBC primary tumor n, HBCx-n, HBC xenograft tumor n.