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Table 3 Odds of having advanced breast cancer among women with breast cancer, each variable adjusted for all others

From: Trends in incidence and detection of advanced breast cancer at biennial screening mammography in The Netherlands: a population based study

 

Advanced vs. non-advanced

screen detected cancers

Advanced vs. non-advanced

interval cancers

 

OR

95%CI

P-value

OR

95%CI

P-value

Age

      

   50-59

1

0.57-0.95

0.02

1

0.80-2.48

0.2

   60-69

0.73

0.61-1.12

0.2

1.41

0.33-1.52

0.4

   70+

0.83

  

0.71

  

Family history of breast cancer

      

   No

1

0.93-1.56

0.16

1

0.66-2.33

0.5

   Yes

1.20

  

1.24

  

Previous breast surgery

      

   No

1

0.64-1.26

0.5

1

0.41-2.04

0.8

   Yes

0.90

  

0.90

  

Use of hormone replacement therapy

      

   No

1

0.80-1.68

0.4

1

1.22-7.53

0.02

   Yes

1.16

  

3.04

  

Initial screen

      

   No

1

0.88-1.61

0.2

1

0.41-2.04

0.8

   Yes

1.19

  

0.91

  

Interval between 2 latest screens

      

< 30 months

1

  

-

  

≥ 30 months

1.63

1.07-2.48

0.02

   

Breast density at latest screening mammogram

      

≤ 50%

1

  

1

  

> 50%

1.25

0.99-1.57

0.06

1.03

0.62-1.72

0.9

Mammographic abnormality

      

   Density

1

  

1

  

   Microcalcifications

0.20

0.14-0.29

0.0001

1.41

0.64-3.13

0.4

   Density with microcalcifications

1.24

0.91-1.69

0.2

0.39

0.11-1.42

0.2

   Architectural distortion

1.49

0.82-2.72

0.2

0.98

0.35-2.73

1.0

   Breast parenchyma asymmetry

0.79

0.23-2.66

0.7

1.43

0.52-3.94

0.5

Tumor histology of invasive cancers1

      

   Ductal

1

  

1

  

   Lobular

2.00

1.44-2.78

0.0001

1.48

0.70-3.14

0.3

   Mixed ductal-lobular

1.55

0.97-2.48

0.07

0.65

0.20-2.06

0.5

   Invasive other

0.63

0.39-1.02

0.07

0.84

0.21-3.32

0.8

   Unknown

1.70

0.23-12.3

0.6

-2

  
  1. 1. Calculated for invasive cancers only. 2. Not calculated because all 4 patients with unknown histology had advanced breast cancer