| Advanced vs. non-advanced screen detected cancers | Advanced vs. non-advanced interval cancers | ||||
---|---|---|---|---|---|---|
 | OR | 95%CI | P-value | OR | 95%CI | P-value |
Age | Â | Â | Â | Â | Â | Â |
   50-59 | 1 | 0.57-0.95 | 0.02 | 1 | 0.80-2.48 | 0.2 |
   60-69 | 0.73 | 0.61-1.12 | 0.2 | 1.41 | 0.33-1.52 | 0.4 |
   70+ | 0.83 |  |  | 0.71 |  |  |
Family history of breast cancer | Â | Â | Â | Â | Â | Â |
   No | 1 | 0.93-1.56 | 0.16 | 1 | 0.66-2.33 | 0.5 |
   Yes | 1.20 |  |  | 1.24 |  |  |
Previous breast surgery | Â | Â | Â | Â | Â | Â |
   No | 1 | 0.64-1.26 | 0.5 | 1 | 0.41-2.04 | 0.8 |
   Yes | 0.90 |  |  | 0.90 |  |  |
Use of hormone replacement therapy | Â | Â | Â | Â | Â | Â |
   No | 1 | 0.80-1.68 | 0.4 | 1 | 1.22-7.53 | 0.02 |
   Yes | 1.16 |  |  | 3.04 |  |  |
Initial screen | Â | Â | Â | Â | Â | Â |
   No | 1 | 0.88-1.61 | 0.2 | 1 | 0.41-2.04 | 0.8 |
   Yes | 1.19 |  |  | 0.91 |  |  |
Interval between 2 latest screens | Â | Â | Â | Â | Â | Â |
< 30 months | 1 | Â | Â | - | Â | Â |
≥ 30 months | 1.63 | 1.07-2.48 | 0.02 |  |  |  |
Breast density at latest screening mammogram | Â | Â | Â | Â | Â | Â |
≤ 50% | 1 |  |  | 1 |  |  |
> 50% | 1.25 | 0.99-1.57 | 0.06 | 1.03 | 0.62-1.72 | 0.9 |
Mammographic abnormality | Â | Â | Â | Â | Â | Â |
   Density | 1 |  |  | 1 |  |  |
   Microcalcifications | 0.20 | 0.14-0.29 | 0.0001 | 1.41 | 0.64-3.13 | 0.4 |
   Density with microcalcifications | 1.24 | 0.91-1.69 | 0.2 | 0.39 | 0.11-1.42 | 0.2 |
   Architectural distortion | 1.49 | 0.82-2.72 | 0.2 | 0.98 | 0.35-2.73 | 1.0 |
   Breast parenchyma asymmetry | 0.79 | 0.23-2.66 | 0.7 | 1.43 | 0.52-3.94 | 0.5 |
Tumor histology of invasive cancers1 | Â | Â | Â | Â | Â | Â |
   Ductal | 1 |  |  | 1 |  |  |
   Lobular | 2.00 | 1.44-2.78 | 0.0001 | 1.48 | 0.70-3.14 | 0.3 |
   Mixed ductal-lobular | 1.55 | 0.97-2.48 | 0.07 | 0.65 | 0.20-2.06 | 0.5 |
   Invasive other | 0.63 | 0.39-1.02 | 0.07 | 0.84 | 0.21-3.32 | 0.8 |
   Unknown | 1.70 | 0.23-12.3 | 0.6 | -2 |  |  |