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Table 2 Characteristics of women with breast cancer

From: Trends in incidence and detection of advanced breast cancer at biennial screening mammography in The Netherlands: a population based study

 

Screen detected cancer

Interval cancer

 

Advanced

N = 570

Non-advanced

N = 1,164

P-

value

Advanced

N = 424

Non-advanced

N = 233

P-

value

Mean age, years (95%CI)

62.0 (61.3 - 62.6)

62.4 (62.0 - 62.8)

0.24

59.5 (58.9 - 60.2)

59.3 (58.4 - 60.2)

0.76

Family history of breast cancer±, No (%)

123 (21.6)

218 (18.7)

0.16

76 (17.9)

43 (18.5)

0.87

Previous breast surgery#

58 (10.0)

130 (11.2)

0.53

72 (15.6)

34 (15.0)

0.43

Use of hormone replacement therapy, No (%)

59 (10.4)

95 (8.2)

0.13

70 (13.1)

20 (6.3)

0.005

Initial screens, No (%)

106 (18.6)

183 (15.7)

0.13

64 (13.5)

32 (11.8)

0.64

Interval between 2 latest screens, No (%)

  

0.08

-

-

 

< 30 months

527 (92.5)

1,101 (94.6)

    

≥ 30 months

43 (7.5)

63 (5.4)

    

Breast density at latest screening mammogram, No (%)

  

0.45

  

0.49

≤ 50%

375 (65.8)

787 (67.4)

 

243 (60.7)

140 (60.1)

 

> 50%

195 (34.2)

377 (32.4)

 

181 (39.3)

93 (39.9)

 

Mammographic abnormality, No (%)

  

< 0.001

  

0.04

   Density

426 (74.8)

740 (63.6)

 

133 (64.6)

78 (70.9)

 

   Microcalcifications

35 (6.1)

280 (24.1)

 

26 (12.6)

18 (16.4)

 

   Density with microcalcifications

82 (14.4)

112 (9.6)

 

16 (7.8)

6 (5.5)

 

   Architectural distortion

22 (3.9)

24 (2.1)

 

11 (5.3)

7 (6.4)

 

   Breast parenchyma asymmetry

4 (0.9)

8 (0.7)

 

20 (9.7)

1 (0.9)

 

Breast cancer visible at previous screening mammogram

199 (42.9)*

418 (42.7)Â¥

0.95

208 (47.6)

112 (47.4)

0.81

Tumor histology of invasive cancers, No (%)

  

< 0.001

  

0.09

   Ductal

414 (72.6)

682 (77.7)

 

304 (71.8)

155 (77.7)

 

   Lobular

93 (16.3)

85 (9.7)

 

87 (21.3)

30 (10.9)

 

   Mixed ductal-lobular

37 (6.5)

41 (4.7)

 

18 (4.0)

10 (5.9)

 

   Invasive other

24 (4.2)

68 (7.7)

 

11 (2.0)

11 (5.5)

 

   Unknown

2 (0.4)

2 (0.2)

 

4 (0.9)

0 (0.0)

 
  1. ±At least one first-degree relative (mother, sister, daughter) with a diagnosis of breast cancer before the age of 50 years or at least two second-degree relatives with breast cancer. #Surgery for benign conditions (e.g., excisional biopsy, breast reduction, breast augmentation, mastitis) and malignant conditions (lumpectomy, mastectomy). *464 subsequent screens; ¥979 subsequent screens
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Breast Cancer Research

ISSN: 1465-542X

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