Table 5 Cox proportional hazards analysis for predictors of BCSS and DMFS in luminal BC valida-tion set: effect of Ki-67LI, MS, tumor grade, nodal stage, tumor size, and adjuvant therapy

Ki-67LI

0.019

0.031

   Low

   Moderate

0.028

1.945 (1.076-3.513)

0.258

1.319 (0.816-2.132)

   High

0.005

2.679 (1.347-5.330)

0.013

2.097 (1.171-3.754)

Mitosis scores

0.028

0.015

   1

   2

0.043

1.403 (0.723-2.723)

0.055

1.228 (0.801-2.002)

   3

0.033

2.096 (0.938-4.687)

0.018

1.854 (0.919-3.741)

Tumor grade

0.022

0.024

   1

   2

0.016

1.379 (0.647-2.938)

0.041

1.604 (0.878-2.930)

   3

0.014

1.595 (0.621-4.096)

0.017

1.566 (0.909-3.459)

Nodal stage

0.001

0.001

Node negative

   1 to 3 positive LN

0.001

1.969 (1.331-2.913)

0.003

1.839 (0.297-2.607)

   ≥ 4 positive LN

0.002

3.498 (2.069-5.915)

0.005

3.330 (2.070-5.358)

Tumor size

0.221

1.262 (0.869-0.834)

0.019

1.492(1.067-2.087)

Endocrine therapy (No/Yes)

0.378

0.553 (0.324-0.499)

0.961

0.998 (0.904-1.101)

Chemotherapy (No/Yes)

0.030

0.768 (0.451-0.309)

0.061

0.636 (0.397-1.021)