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Table 2 Patient and tumour characteristicsa

From: Lack of EGFR-activating mutations in European patients with triple-negative breast cancer could emphasise geographic and ethnic variations in breast cancer mutation profiles

Patient and tumour characteristics

Number of patients (%)

(N= 229)

Patient age

Median age at diagnosis, years [range]

 

58 [29 to 84]

Tumour classification

  

   T1

88 (38)

 

   T2

109 (48)

 

   T3

9 (4)

 

   T4

21 (9)

 

   TX

2 (1)

 

Node classification

  

   N0

136 (59)

 

   N1

47 (21)

 

   N2

20 (9)

 

   N3

8 (3)

 

   NX

18 (8)

 

Metastasis classification

  

   M0

212 (92)

 

   M1

13 (6)

 

   MX

4 (2)

 

Histology

  

   Ductal

180 (79)

 

   Lobular

14 (6)

 

   Otherb

35 (15)

 

SBR grade

  

   I

9 (4)

 

   II

70 (31)

 

   III

146 (64)

 

   NE

4 (2)

 

Tubule formation

  

   1

5 (2)

 

   2

31 (14)

 

   3

178 (78)

 

   NE

15 (6.55)

 

Nuclear pleomorphism

  

   1

5 (20)

 

   2

66 (29)

 

   3

102 (44)

 

   NE

16 (7)

 

Mitotic count

  

   1

45 (20)

 

   2

66 (29)

 

   3

102 (44)

 

   NE

16 (7)

 

Peritumoural vascular invasion

  

   Yes

115 (50)

 

   No

53 (23)

 

   NE

61 (27)

 
  1. aMX = no clinical data regarding metastatic spreading; NE = not evaluated; NX = no clinical data regarding nodal status; TX = no clinical data regarding tumour size. bNine undifferentiated carcinomas, six invasive papillary carcinomas, four mixed ductal-lobular carcinomas, three apocrine carcinomas, four medullary carcinomas, three metaplastic carcinomas, two sarcomatoid carcinomas, two adenoid cystic carcinomas, and one case each of the following histological subtypes: adenosquamous and neuroendocrine.