Figure 3

Additional TIL subsets and their relationship with CD3 status and anthracycline sensitivity. (a) TIL levels in CD3-high and -low cases. Data represent average numbers of TIL expressing CD8, CD4, or CD20 ±SEM. ***P < 0.0001, Mann-Whitney t test. (b) Association of CD8⁺ and (c) CD4⁺ TIL with response to anthracycline therapy. Patients were categorized according to levels of CD8⁺ and CD4⁺ TIL and assessed for disease-free survival (DFS) with respect to anthracycline-based therapy.