Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases

Breast Cancer Research

Table 4

Univariable analyses									Multivariable analyses
	OS		TTDR		TTCNS		OS CNS		OS		TTDR		TTCNS		OS CNS
Variable	HR	P	HR	P	HR	P	HR	P	HR	P	HR	P	HR	P	HR	P
PTEN (H score, negative vs. positive)	1.7	0.16	2.2	0.025	1.8	0.07	0.95	0.9	1.9	0.1	2.4	0.02	2	0.06	0.93	0.86
Subtype (TN vs. non-TN)	3.1	0.003	1.9	0.04	1.8	0.06	3.2	0.003	3.2	0.002	2	0.04	1.8	0.06	3.2	0.003

ISSN: 1465-542X