Figure 7
From: Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases
Evaluation of PTEN gene expression in breast cancer samples from two publicly available data sets [19, 20]. (a) PTEN expression across the intrinsic molecular subtypes of 855 primary tumors of the combined cohort in Harrell et al. [19]. (b) PTEN expression in a panel of unpaired breast cancer brain metastases (n = 7) and other distant sites (n = 29). The colored boxes represent the interquartile range (IQR); the bar indicates the median value; whiskers show the 1.5 × IQR.