Table 2 CHEK2 mutations were more frequent in cases than in controls
From: CHEK2 contribution to hereditary breast cancer in non-BRCAfamilies
CHEK2mutation type | Controls (n= 1,026)a | Allelic frequency in controls | Cases (n= 1,014)a | Allelic frequency in cases | P value | OR | 95% CI |
|---|---|---|---|---|---|---|---|
Any CHEK2 mutation | 4 | 0.39% | 16 | 1.58% | 0.0065 | 4.15 | (1.38 to 12.50) |
CHEK2 deleterious mutations | 3 | 0.29% | 15 | 1.48% | 0.0042 | 5.18 | (1.49 to 18.00) |