Figure 5

Binding of nanoparticles to MCF7/Her2-18 tumors grown in mice. (a) Excised tumors were injected with anti-Her2 antibody-conjugated nanoparticles or unconjugated nanoparticles (no Ab) and examined by SQUID. Data represent the mean and standard error measurement of four experiments (P = 0.049). (b) Photomicrographs of injected tissue with anti-Her2 or no Ab nanoparticles at magnifications of 100× (left) and 400× (right). Scale bars = 100 μM (left) and 25 μM (right). Her2, human epidermal growth factor-like receptor 2; SQUID, Superconducting Quantum Interference Device.