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Figure 1 | Breast Cancer Research

Figure 1

From: Quantitative copy number analysis by Multiplex Ligation-dependent Probe Amplification (MLPA) of BRCA1-associated breast cancer regions identifies BRCAness

Figure 1

Survival analysis. Association of BRCA1-like classification with array Comparative Genomic Hybridisation (aCGH) and with Multiplex Ligation-dependent Probe Amplification (MLPA), with outcome after intensive alkylating chemotherapy and conventional dose chemotherapy. Kaplan-Meier survival curves according to the BRCA1 classification of tumours. The patients had been randomly assigned to either intensified dose chemotherapy or conventional dose chemotherapy. (a) Recurrence-free survival (RFS) of Sporadic-like CGH triple-negative (TN) patients (log rank test: P = 0.543), (b) RFS of BRCA1-likeCGH TN patients (P = 0.002), (c) RFS of Sporadic-like MLPA TN patients (P = 0.625), (d) RFS of BRCA1-like MLPA TN patients (P = 0.024).

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